Overall the center aims at providing thought-leadership, assisting current and future networks of science diplomacy, and developing options.

The Science Diplomacy Center collaborates closely with science and technology (S&T) advisor networks, especially the Foreign Minister Science and Technology Advisor Network (FMSTAN). The S&T advisor collaborations also will involve the International Network for Government Science Advice (INGSA) under the aegis of the International Council of Science (ICSU).

Further, the Science Diplomacy Center will continue to build collaboration with the Science and Technology Diplomatic Circle (S&TDC), which is a new association involving more than fifty diplomatic missions and affiliated consular organizations in Boston, Massachusetts.

The center will develop collaboration with international institutions that touch the natural and social sciences (e.g. ICSU, which formally began merging with the International Social Science Council -ISSC, in 2016) – which both observe and interpret change over time and space (bio-geophysical to socio-economic) –discovering and integrating  options with societal relevance for informed decision-making.